It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. Erythritol: Is This Healthy Sweetener the Real Deal? It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. Ginkgo biloba has been widely cultivated across the globe for a variety of uses, most of which are medicinal. We don't yet know what the best dose to use is, but studies have used two 50 mg Pycnogenol capsules per day. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. . 2005 - 2023 WebMD LLC. As I mentioned, pine bark extract is superior when it comes to antioxidants. Remember to speak with a doctor before taking Pycnogenol. Certain studies used combination products, so its unknown what the contribution of Pycnogenol itself was. Rakel, D. Integrative Medicine, 3rd edition, Saunders, 2012. But a month after pycnogenol was stopped, the symptoms came back, suggesting that it may need to be used regularly to achieve the benefits [41]. Prenatal nutrition can be confusing. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. In the control group, there were five thrombotic events; whereas the Pycnogenol-treated subjects only experienced nonthrombotic, local flare-ups. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. Pycnogenol acts as a sustained-release formulation. Considering that about 1 of 3 adults in the U . Score one for diabetes control and fewer risk factors for the heart. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. This bark extract has been around for about 450 years. Your email address will not be published. Moreover, Pycnogenol group either reduced or discontinued the use of asthma drugs. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. Disclaimer: Results are not guaranteed*** and may vary from person to person***. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for . Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. The study showed that many people who participated had a drop in their systolic blood pressure after taking Pycnogenol. A combination product with Pycnogenol (Lady Prelox) improved sexual function in a clinical trial of 83 healthy postmenopausal women after 8 weeks. It seems to lower blood pressure and improve blood flow to the legs. According to a study in 59 cancer patients, Pycnogenol (150 mg/day) may reduce side effects associated with radiation or chemotherapy, including mouth soreness and ulcers, mouth and eye dryness, nausea, vomiting, diarrhea and weight loss [78]. Any medication that you take, including herbal supplements, comes with certain risks. Studies have found that nattokinase thins the blood and dissolves accumulated solids in it. 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However, with the addition of twice-daily Pycnogenol, normal erection increased to 80%, which further increased to 92.5% during the third month on thrice-daily Pycnogenol. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. This plant extract also shows promise in such far-flung conditions as traumatic brain injury 40,41, skin problems 37, pain syndromes 38,39, and even tinnitus . There's good evidence that pycnogenol helps with eye damage caused by diabetes. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. Trees of this pine have been naturalized in Australia and New Zealand, where most Enzogenol is now made [7]. DOI: Gulati OP. Pycnogenol treatment led to significantly better improvement in the lung function and asthma symptoms. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Prunes and prune juice have many health benefits. Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. Add to Cart. 3. It can also be used for local application on the skin without the risk of side effects. We all know the power of antioxidants to improve health and thehigh-antioxidant foodswe should eat regularly. Risks. Pycnogenol (150 mg/day) reduced pain in a study of 100 people with osteoarthritis after 3 months. A trial of 84 people found that both Pycnogenol oral supplements and creams (0.5%) may prevent hemorrhoids from bleeding during acute attacks after 7 days. One study suggests that Pycnogenol has no effect when given just 3 weeks beforehand, as it possibly requires a lag time to stabilize the immune response [17]. The specific tree from which the bark is extracted is called a maritime pine. Pycnogenol effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women [Abstract]. Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. Pycnogenol; Pycnogenol. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? Abdominal pain was by far the most . Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. Not bad. (14, 15). However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. DOI: Luzzi R, et al. but is for informational and educational purposes alone. Pycnogenol led to a reduction of muscle cramps from 4.8 a week to 1.3 at week four. The results showed that the combination of local and systemic applications of Pycnogenol were the best in terms of ulcer healing even though local application of Pycnogenol also speeded up ulcer healing. Ana spent years working with patients who suffer from various mental health issues and chronic health problems. That said, there are some instances where this extract may possibly be effective. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. In addition to general healthy eating, some specific vitamins and minerals may help improve ADHD. Pycnogenol seems well-tolerated for use in adults for up to 6 months. In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Research indicates that Pycnogenol provides an increase in survival performance of train athletes. Required fields are marked *. We do not aim to diagnose, treat, cure or prevent any illness or disease. Pycnogenol is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins . In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. Because of its anti-inflammatory effects, nattokinase has been used to help with pain from arthritis, including that of rheumatoid arthritis. Placebo capsules were given to control subjects at the same times. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. Researchers suggest it may boost sustained attention, memory, executive functions, mood, and reduce oxidative stress [19]. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. Sort By. Chestnut seed extract did not do as well. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. A trial of 132 people found that Pycnogenol (150 mg/day) may improve risk factors of metabolic syndrome including lowering triglyceride levels, blood pressure, and fasting glucose, decreasing waist circumference, and increasing HDL cholesterol levels [29]. It is found primarily in southwestern France and is used to help people with asthma, allergies, hay fever, and other health conditions.. According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. A new peer-reviewed study, published in the Bratislava Medical Journal, shows that daily supplementation with the natural antioxidant, Pycnogenol, a French maritime pine bark extract, can improve the symptoms of ED.. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. Moreover, Pycnogenol lowered the chemical, leukotrienes responsible for asthma attacks. One study involved a four-week treatment period followed by one week of no treatment or observation period. Researchers suggest that it may epigenetically turn off genes responsible for joint damage (ADAMTS) as well as reduce inflammation enzymes (MMP3) and cytokines (IL 1-beta) [47, 48]. American Cancer Society: "Pine Bark Extract.". During week, five without, treatment, reduction of cramps was maintained in all three groups. SelfDecode does not treat, diagnose or cure any conditions, Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. It should never be used as a replacement for approved medical therapies. Ask your doctor for advice. Results showed that one month of Pycnogenol led to a significant reduction of hyperactivity with improvement in attention and visual-motor coordination and concentration, as compared to no positive effects in the placebo group. Blood clots form as a result of platelet aggregation, which is the platelets in the blood clumping together. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. 5) Inflammation and Allergies. Thirty patients with diabetic ulcers were treated with 150 mg Pycnogenol daily for four weeks and another group of 30 comparable patients received no treatment. This article explains which supplements are believed to be safe during pregnancy and which ones you should avoid. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. A clinically studied blend of Pycnogenol and a special bilberry extract (called Mirtogenol ) has been shown to provide benefits for vision and eye health. Possess Anti-Inflammatory Action. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. Researchers suggest that Pycnogenol may reduce cough, night-awakenings, improve airway flow, and the need for additional asthma medication [16]. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. She loves communicating science and empowering people to achieve their optimal health. Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. Pycnogenol is thought to be an antioxidant that helps protect cells from damage. Pycnogenol is considered possibly safe when taken orally or when applied topically as a cream or ointment. Animal studies have found that gotu kola makes it harder . This nerve affects our balance and hearing by sending signals to the brain. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. returned. In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. Pycnogenol significantly reduced the swelling as well as the feeling of heaviness. Pycnogenol-treated patients reported significant improvement with knee pain, as compared to the placebo group. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [58, 59]. For allergies: 50 milligrams twice daily. Pycnogenol can help control blood pressure, which helps improve overall heart health. Note that the numbers in parentheses (1, 2, etc.) There is limited evidence that it could be used in treating Attention Deficit Hyperactivity Disorder (ADHD). A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. WebMD does not provide medical advice, diagnosis or treatment. Pine bark distill has been studied regarding its relationship to exercise performance, oxidative stress and excitement to torso that has been imposed by exercise. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. 7. In contrast, bleeding still occurred in the control group [61]. Another group of men who took just l-arginine didnt improve [66]. Asthma is caused by inflammation in the lungs, which makes it hard to breathe. Note that each number in parentheses [1, 2, 3, etc.] Pycnogenol was gradually increased to 120 mg/day over this time period, while the l-arginine was maintained at 1.7 g/day throughout. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . The outcome showed significant healing when compared to those subjects who were not given any drug or remedy, concluding that Pycnogenol may be an effective remedy for healing of surgery-related lesions. Pycnogenol (100 mg/day) improved menopausal symptoms and quality of life in a clinical trial of 35 women after 8 weeks [68]. Regardless, a natural option is available and far worth the wait. The treatment was four 50 mg capsules of Pycnogenol. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. Its true. In another study, Pycnogenol increased glutathione levels and total antioxidants after a month in children with ADHD [42, 43]. Posted on Thursday, August 14, 2014 The majority of this article is information obtained from the book "All About DIM" by Michael A. Zeligs, MD and A. Scott Connelly, MD. Can Pycnogenol help? A 2021 review in the Arab Journal of Urology listed it first among "promising herbal remedies" for ED. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . The dosage in most clinical studies varied between 50-360 mg/day. A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. Used early on, it may prevent eye damage and blindness from diabetes [34]. The combination of L-arginine and Pycnogenol may help in erectile dysfunction by boosting nitric oxide, which potentially could improve blood flow in men [66]. One study found that Pycnogenol may reduce the activity of the inflammatory enzymes COX1 and COX2, similar to how NSAID drugs work. Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. In a third study, 19 men with fertility problems were given 200 mg Pycnogenol daily for 90 days. (2015). blood in the urine. It can then lead to heart problems like stroke or heart attack. A 2004 animal study also found that applying a gel containing pine bark extract sped up the wound-healing process. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for treating conventional diabetes may be beneficial. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. Neuroprotective effect of Pycnogenol® following traumatic brain injury. Finally, research suggests that Pycnogenol may improve triathlon time while possibly reducing cramps and post-running pain [10]. Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. Work with your pediatrician to see if there are contraindications for each child. However, it can also be used topically. Pycnogenol also treatment improved blood vessel function. Make sure to seek out the advice of your physician prior to using pine bark extract or the branded name, Pycnogenol. But what are its health benefits? Natural Factors Pycnogenol 100mg 30 Veggie Caps. Top 9 Natural Allergy Relief Home Remedies - Dr. Axe 1 week ago from draxe.com Eat an Anti-Inflammatory, Alkaline Diet. According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. More specifically, because it strengthens the capillaries in the retina, Mirtogenol can help prevent retinopathy. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10.
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